BDBM50113851 (+/-)-Tranylcypromine::2-PCPA::2-Phenyl-cyclopropylamine::2-phenylcyclopropanamine::CHEMBL313833::TRANYLCYPROMINE::Tranylcypromine,(+)::Tranylcypromine,(-)::US8609708, 6 Tranyl- cypromine::US8609708, 6 Tranylcypromine

SMILES NC1CC1c1ccccc1

InChI Key InChIKey=AELCINSCMGFISI-UHFFFAOYSA-N

Data  13 KI  33 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50113851   

TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
Waseda University

Curated by ChEMBL
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)
Affinity DataIC50:  2.30E+6nMAssay Description:Inhibition of recombinant human LSD2 using H3K4 peptide as substrate assessed as decrease in H3K4 demethylation after 1 hr by mass spectroscopic anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 2(Homo sapiens (Human))
Waseda University

Curated by ChEMBL
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human full length LSD2 using biotin-labeled H3K4me2 (1 to 24 residues) as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed